REGULATION OF CTCF LOOP FORMATION DURING PANCREATIC CELL DIFFERENTIATION

Abstract Transcription reprogramming during cell differentiation involves targeting enhancers to genes responsible for establishment of cell fates.To understand the contribution of CTCF-mediated chromatin organization to cell lineage commitment, we analyzed 3D chromatin architecture during the differentiation of human embryonic stem cells into panc

The deep marine subsurface is a vast habitat for microbial life where cells may live on geologic timescales.Because DNA in sediments may be preserved on Board shorts long timescales, ribosomal RNA (rRNA) is suggested to be a proxy for the active fraction of a microbial community in the subsurface.During an investigation of eukaryotic 18S rRNA by am